The Cardinals (1-19, 0-10), down nine at halftime, were done in by a 25-point fourth quarter by Highland.
Keenon Garcia knocked in 13 points, Jonathan McClure canned 12 and Edward Arellano and Shane Berry contributed eight each.
The Lady Cardinals were stifled offensively Tuesday, scoring just seven first-half points in a 55-26 defeat to Highland.
The Hermleigh girls (6-14, 1-9) got 12 from Alana Culp and six from Alicia Culp.
Amy Botts added four and Brittany Jones and Brittney Kelly each connected for two.